بررسی نقش پیش گویی کننده Heart Rate Recovery در تشخیص CAD بارز

Abstract Background: Cardiovascular disease and coronary disease is at the top of the main causes of death in developed and developing countries. In many studies have been done in recent years, the role of heart rate recovery (HRR) as a predictor of mortality in patients with efficient factor for coronary artery disease (CAD) and vascular involvement are well known. In this research relationship between HRR and significant CAD has been studied. Materials and methods: This research is a diagnostic study. In this study patients from 2012/15/2to 2013/15/2 due to chest pain were referred to Loghman Hakim hospital were studied. Patients with atypical chest pain and positive exercise test underwent angiography. If the exercise test was negative nuclear scan also requested. If nuclear scan was negative, patients were considered Non-CAD. Patients with positive scan underwent coronary angiography. After exercise test HRR in minutes 1 and 2 was calculated. An independent interventionist who was unaware about ETT results interpreted angiographic results. Results: In this study, a total of 106 patients were studied who 41 patients(38.7%) were female and 65 patients(61.3%)were male.11 patients(10%) had abnormal HRR1 and 8 patients(8%) had abnormal HRR2.25 patients(23.6%)had significant CAD in angiography and 81 patients(76.4%) had non-significant CAD. Conclusion: Positive predictive value of first minute HRR was 83.2% and negative predictive value was 81.8% and for second minute HRR time it was 80.6% and 75% sequentially and p-value was<0.9.It seems that there is no relationship between HRR and CAD and we can’t use HRR to predict significant CAD at least in this time. Keywords: Exercise test, Coronary artery disease, Angiography.